This community is the southern terminus for Ontario Highway 6; located 480 kilometres (300 mi) to the south of the Northern Ontario community of McKerrow. This highway stretches northward as a two-lane, undivided highway until the traffic flow increases to four lanes shortly after it departs from Caledonia. In addition to allowing Port Dover residents direct access to the city of Hamilton, it also briefly merges with Highway 403 to allow for access to the Royal Botanical Gardens and locations on to Toronto.

The postal forward sortation area is N0A; sharing its Canada Post service with the western portion of Haldimand County. All residences and businesses within the Port Dover area have a 583 in their phone number.

Sightings of at least 128 bird species have been verified in Port Dover from 1956 to 2019; including the Indigo bunting, the Rose-breasted grosbeak, and the Scarlet tanager.